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The antibody against NAT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human NAT1 (NP_001153646.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NAT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human NAT1 (NP_001153646.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04935A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NAT1 |
| Target Synonyms | AAC1; MNAT; NATI; NAT-1; NAT1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | U-937 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human NAT1 (NP_001153646.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P18440 | Immunogen Sequence |
Uniprot Id
P18440
Target Species
Human
Target Name
NAT1
Target Full Name
Arylamine N-acetyltransferase 1
Target Function
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Arylamine N-acetyltransferase family
Target Synonyms
AAC1 ; ARY1_HUMAN; Arylamide acetylase 1; Arylamine N acetyltransferase 1; Arylamine N-acetyltransferase 1; mNAT; Monomorphic arylamine N acetyltransferase; Monomorphic arylamine N-acetyltransferase; N acetyltransferase type 1; N-acetyltransferase type 1; NAT 1; NAT-1; nat1; NATI
Target Background
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
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