Rabbit anti-Human NINL Polyclonal Antibody

The antibody against NINL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human NINL (NP_079452.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02419A

Number

Cat.No	ADA-02419A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NINL
Target Synonyms	NLP; NINL	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse testis	Application	ELISA, WB

Cat.No

ADA-02419A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NINL

Target Synonyms

NLP; NINL

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse testis

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human NINL (NP_079452.3).	Target Species	Human
Immunogen Sequence	MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSC	Uniprot ID	Q9Y2I6

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human NINL (NP_079452.3).

Target Species

Human

Immunogen Sequence

MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSC

Uniprot ID

Q9Y2I6

Background Information

Uniprot Id

Q9Y2I6
Target Species

Human
Target Name

NINL
Target Full Name

Ninein-like protein
Target Function

Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis.
Target Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Note=In interphase cells, NINL is transported to the centrosomes by the dynein-dynactin motor complex (PubMed:16254247). During centrosome maturation, PLK1 directly phosphorylates NINL resulting in its release into the cytoplasm (PubMed:16254247).
Target Tissue Specificity

Expressed in KYSE-150 esophageal carcinoma, HeLa cervical carcinoma and U2OS osteosarcoma cells. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase (at protein level). Expressed in fetal heart, skeletal muscle, liver, lun
Target Synonyms

NINL; KIAA0980; NLP; Ninein-like protein
Target Background

Predicted to enable calcium ion binding activity. Predicted to be involved in microtubule anchoring at centrosome. Located in cytosol; intercellular bridge; and microtubule cytoskeleton.

Rabbit anti-Human NINL Polyclonal Antibody

Specifications

Immunogen Information

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