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Rabbit anti-Human NR2F2 Polyclonal Antibody

The antibody against NR2F2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human NR2F2 (NP_066285.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-10910A

The antibody against NR2F2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human NR2F2 (NP_066285.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-10910A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNR2F2
Target SynonymsARP1; ARP-1; CHTD4; NF-E3; SRXX5; SVP40; COUPTF2; COUPTFB; TFCOUP2; COUPTFII; NR2F2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesC6, MCF7, Molt-4(Negative control), Mouse liver, PC-12ApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human NR2F2 (NP_066285.1).Target SpeciesHuman
Immunogen SequenceMAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKUniprot IDP24468
Background Information
  • Uniprot Id

    P24468

  • Target Species

    Human

  • Target Name

    NR2F2

  • Target Full Name

    COUP transcription factor 2

  • Target Function

    Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development.

  • Target Involvement

    Congenital heart defects, multiple types, 4 (CHTD4)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Nuclear hormone receptor family, NR2 subfamily

  • Target Tissue Specificity

    Ubiquitous. Expressed in the stromal cells of developing fetal ovaries.

  • Target Synonyms

    Apolipoprotein A-I regulatory protein 1; Apolipoprotein AI regulatory protein 1; ARP-1; ARP1; COT2_HUMAN; COUP TF2; COUP transcription factor 2; COUP transcription factor II; COUP-TF II; COUP-TF2; NR2F2; Nuclear receptor subfamily 2 group F member 2

  • Target Background

    This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants.

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