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Rabbit anti-Human NRD1 Polyclonal Antibody

The antibody against NRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human NRD1 (NP_001095132.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13647A

The antibody against NRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human NRD1 (NP_001095132.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-13647A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNRD1
Target SynonymsNRD1; hNRD1; hNRD2; D1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293TApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human NRD1 (NP_001095132.1).Target SpeciesHuman
Uniprot IDO43847Immunogen Sequence
Background Information
  • Uniprot Id

    O43847

  • Target Species

    Human

  • Target Name

    NRDC

  • Target Full Name

    Nardilysin

  • Target Function

    Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.

  • Target Protein Families

    Peptidase M16 family

  • Target Tissue Specificity

    Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues.

  • Target Synonyms

    NRDC; NRD1; Nardilysin; EC 3.4.24.61; N-arginine dibasic convertase; NRD convertase; NRD-C; Nardilysin convertase

  • Target Background

    This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

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