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The antibody against NUDT9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human NUDT9 (NP_076952.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NUDT9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human NUDT9 (NP_076952.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02252A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NUDT9 |
| Target Synonyms | NUDT10; NUDT9 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat heart, Mouse brain, Mouse testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human NUDT9 (NP_076952.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BW91 | Immunogen Sequence |
Uniprot Id
Q9BW91
Target Species
Human
Target Name
NUDT9
Target Full Name
ADP-ribose pyrophosphatase, mitochondrial
Target Function
Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.
Target Subcellular Location
[Isoform 1]: Mitochondrion.
Target Protein Families
Nudix hydrolase family, NudF subfamily
Target Tissue Specificity
Ubiquitously expressed but isoform 1 is the most predominant isoform.
Target Synonyms
Adenosine diphosphoribose pyrophosphatase; ADP ribose diphosphatase; ADP ribose phosphohydrolase; ADP ribose pyrophosphatase, mitochondrial precursor; ADP ribose pyrosphosphatase NUDT9; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase, mitochondrial; ADPR PPase; ADPR-PPase; EC 3.6.1.13; Nucleoside diphosphate linked moiety X motif 9; Nucleoside diphosphate linked moiety X type motif 9; Nucleoside diphosphate-linked moiety X motif 9; Nudix (nucleoside diphosphate linked moiety X) type motif 9; Nudix hydrolase 9; Nudix motif 9; NUDT10; NUDT9; NUDT9_HUMAN
Target Background
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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