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The antibody against PFKP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 605-784 of human PFKP (NP_002618.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PFKP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 605-784 of human PFKP (NP_002618.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07754A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PFKP |
| Target Synonyms | PFKF; PFK-C; PFK-P; ATP-PFK; PFKP | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, BxPC-3, Jurkat, U-87 MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 605-784 of human PFKP (NP_002618.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | IFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQPWSV | Uniprot ID | Q01813 |
Uniprot Id
Q01813
Target Species
Human
Target Name
PFKP
Target Full Name
ATP-dependent 6-phosphofructokinase, platelet type
Target Function
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Phosphofructokinase type A (PFKA) family, ATP-dependent PFK group I subfamily, Eukaryotic two domain clade "E" sub-subfamily
Target Synonyms
PFKF; PFK-C; PFK-P; ATP-PFK; PFKP
Target Background
This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
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