Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against PRICKLE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 615-844 of human PRICKLE2 (NP_942559.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against PRICKLE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 615-844 of human PRICKLE2 (NP_942559.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-09152A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRICKLE2 |
| Target Synonyms | EPM5; PRICKLE2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 615-844 of human PRICKLE2 (NP_942559.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q7Z3G6 | Immunogen Sequence |
Uniprot Id
Q7Z3G6
Target Species
Human
Target Name
PRICKLE2
Target Full Name
Prickle-like protein 2
Target Involvement
PRICKLE2 mutations have been found in patients with myoclonic epilepsy but involvement of this gene in pathogenesis is under debate since some of the patients also carry POLG mutations.
Target Subcellular Location
Nucleus membrane.
Target Protein Families
Prickle / espinas / testin family
Target Tissue Specificity
Expressed in brain, eye and testis. Additionally in fetal brain, adult cartilage, pancreatic islet, gastric cancer and uterus tumors.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
EPM5; PRIC2; PRIC2_HUMAN; Prickle homolog 2 (Drosophila); Prickle planar cell polarity protein 2; prickle-like 2 (Drosophila); prickle-like 2; Prickle-like protein 2; PRICKLE2
Target Background
This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
