Rabbit anti-Human RAB11FIP4 Polyclonal Antibody

The antibody against RAB11FIP4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 338-637 of human RAB11FIP4 (NP_116321.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04749A

Number

Cat.No	ADA-04749A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RAB11FIP4
Target Synonyms	FIP4-Rab11; RAB11-FIP4; RAB11FIP4	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	U-87MG	Application	ELISA, WB

Cat.No

ADA-04749A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RAB11FIP4

Target Synonyms

FIP4-Rab11; RAB11-FIP4; RAB11FIP4

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 338-637 of human RAB11FIP4 (NP_116321.2).	Target Species	Human
Uniprot ID	Q86YS3	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 338-637 of human RAB11FIP4 (NP_116321.2).

Target Species

Human

Uniprot ID

Q86YS3

Immunogen Sequence

Background Information

Uniprot Id

Q86YS3
Target Species

Human
Target Name

RAB11FIP4
Target Full Name

Rab11 family-interacting protein 4
Target Function

Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
Target Subcellular Location

Endosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle.
Target Tissue Specificity

Present at high level in testis (at protein level). Weakly expressed in other tissues.
Target Synonyms

RAB11FIP4; ARFO2; KIAA1821; Rab11 family-interacting protein 4; FIP4-Rab11; Rab11-FIP4; Arfophilin-2
Target Background

The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma.

Rabbit anti-Human RAB11FIP4 Polyclonal Antibody

Specifications

Immunogen Information

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