Rabbit anti-Human RAP2A Polyclonal Antibody

The antibody against RAP2A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human RAP2A (NP_066361.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04314A

Number

Cat.No	ADA-04314A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RAP2A
Target Synonyms	KREV; RAP2; K-REV; RbBP-30; RAP2A	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse brain, Mouse lung, Raji, SW620, U-87MG	Application	ELISA, WB

Cat.No

ADA-04314A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RAP2A

Target Synonyms

KREV; RAP2; K-REV; RbBP-30; RAP2A

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse brain, Mouse lung, Raji, SW620, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human RAP2A (NP_066361.1).	Target Species	Human
Immunogen Sequence	MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSACNIQ	Uniprot ID	P10114

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human RAP2A (NP_066361.1).

Target Species

Human

Immunogen Sequence

MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSACNIQ

Uniprot ID

P10114

Background Information

Uniprot Id

P10114
Target Species

Human
Target Name

RAP2A
Target Full Name

Ras-related protein Rap-2a
Target Function

Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Target Subcellular Location

Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody.
Target Protein Families

Small GTPase superfamily, Ras family
Target Synonyms

RAP2A; Ras-related protein Rap-2a; RbBP-30
Target Background

Enables GTPase activity; guanyl ribonucleotide binding activity; and magnesium ion binding activity. Involved in several processes, including actin cytoskeleton reorganization; microvillus assembly; and positive regulation of protein autophosphorylation. Acts upstream of or within establishment of protein localization. Located in plasma membrane and recycling endosome membrane.

Rabbit anti-Human RAP2A Polyclonal Antibody

Specifications

Immunogen Information

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