Rabbit anti-Human SERPINB4 Polyclonal Antibody

The antibody against SERPINB4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SERPINB4 (NP_002965.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10107A

Number

Cat.No	ADA-10107A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SERPINB4
Target Synonyms	PI11; SCCA1; SCCA2; LEUPIN; SCCA-2; SERPINB4	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse skin	Application	ELISA, WB

Cat.No

ADA-10107A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SERPINB4

Target Synonyms

PI11; SCCA1; SCCA2; LEUPIN; SCCA-2; SERPINB4

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse skin

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SERPINB4 (NP_002965.1).	Target Species	Human
Immunogen Sequence	RTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP	Uniprot ID	P48594

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SERPINB4 (NP_002965.1).

Target Species

Human

Immunogen Sequence

RTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP

Uniprot ID

P48594

Background Information

Uniprot Id

P48594
Target Species

Human
Target Name

SERPINB4
Target Full Name

Serpin B4
Target Function

May act as a protease inhibitor to modulate the host immune response against tumor cells.
Target Subcellular Location

Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Target Protein Families

Serpin family, Ov-serpin subfamily
Target Tissue Specificity

Squamous cells.
Target Research Area

Cancer
Target Synonyms

Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor (leucine serpin); SCCA 2; SCCA-2; SCCA1; SCCA2; SCCA2/SCCA1 fusion protein; Serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 4; Serpin B4; Serpin peptidase inhibitor; clade B (ovalbumin); member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Target Background

The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.

Rabbit anti-Human SERPINB4 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human SERPINB4 Polyclonal Antibody Now

Related Products