Rabbit anti-Human SLC9A3 Polyclonal Antibody

The antibody against SLC9A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 460-600 of human SLC9A3 (NP_004165.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06925A

Number

Cat.No	ADA-06925A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SLC9A3
Target Synonyms	NHE3; DIAR8; NHE-3; SLC9A3	Form	Liquid
Species Reactivity	Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat kidney	Application	ELISA, WB

Cat.No

ADA-06925A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SLC9A3

Target Synonyms

NHE3; DIAR8; NHE-3; SLC9A3

Form

Liquid

Species Reactivity

Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat kidney

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 460-600 of human SLC9A3 (NP_004165.2).	Target Species	Human
Immunogen Sequence	VQWLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQS	Uniprot ID	P48764

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 460-600 of human SLC9A3 (NP_004165.2).

Target Species

Human

Immunogen Sequence

VQWLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQS

Uniprot ID

P48764

Background Information

Uniprot Id

P48764
Target Species

Human
Target Name

SLC9A3
Target Full Name

Sodium/hydrogen exchanger 3
Target Function

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Target Involvement

Diarrhea 8, secretory sodium, congenital (DIAR8)
Target Subcellular Location

Apical cell membrane; Multi-pass membrane protein.
Target Protein Families

Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family
Target Synonyms

MGC126718; MGC126720; Na(+)/H(+) exchanger 3; NHE 3; NHE-3; NHE3; SL9A3_HUMAN; SLC9A 3; Slc9a3; Sodium / Hydrogen Exchanger 3; Sodium/hydrogen exchanger 3; Sodium/hydrogen exchanger, apical epithelial; Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; Solute carrier family 9 (sodium/hydrogen exchanger), member 3; Solute carrier family 9 member 3
Target Background

The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22.

Rabbit anti-Human SLC9A3 Polyclonal Antibody

Specifications

Immunogen Information

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