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The antibody against SRM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human SRM (NP_003123.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SRM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human SRM (NP_003123.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01766A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRM |
| Target Synonyms | PAPT; SPS1; SPDSY; SRML1; SRM | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 22Rv1, HepG2, Mouse liver, Mouse small intestine, Mouse stomach, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human SRM (NP_003123.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P19623 | Immunogen Sequence |
Uniprot Id
P19623
Target Species
Human
Target Name
SRM
Target Full Name
Spermidine synthase
Target Function
Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.
Target Protein Families
Spermidine/spermine synthase family
Target Research Area
Metabolism
Target Synonyms
OTTHUMP00000002170; PAPT; Putrescine aminopropyltransferase; SPDSY; SPEE_HUMAN; Spermidine synthase 1; Spermidine synthase; SPS1; Srm; SRML1
Target Background
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
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