Rabbit anti-Human THEMIS2 Polyclonal Antibody

The antibody against THEMIS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THEMIS2 (NP_004839.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10104A

Number

Cat.No	ADA-10104A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	THEMIS2
Target Synonyms	ICB1; ICB-1; C1orf38; THEMIS2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, MCF7, Mouse spleen	Application	ELISA, WB

Cat.No

ADA-10104A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

THEMIS2

Target Synonyms

ICB1; ICB-1; C1orf38; THEMIS2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, MCF7, Mouse spleen

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THEMIS2 (NP_004839.2).	Target Species	Human
Uniprot ID	Q5TEJ8	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THEMIS2 (NP_004839.2).

Target Species

Human

Uniprot ID

Q5TEJ8

Immunogen Sequence

Background Information

Uniprot Id

Q5TEJ8
Target Species

Human
Target Name

THEMIS2
Target Full Name

Protein THEMIS2
Target Function

May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production. Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways.
Target Subcellular Location

Nucleus. Cytoplasm.
Target Protein Families

Themis family
Target Tissue Specificity

Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1.
Target Synonyms

Basement membrane induced; Chromosome 1 open reading frame 38; ICB 1; ICB1; Induced by contact to basement membrane 1 protein; Protein ICB 1; Protein ICB-1; Protein THEMIS2; THEMIS2; THMS2_HUMAN; Thymocyte expressed molecule involved in selection protein 2; Thymocyte-expressed molecule involved in selection protein 2
Target Background

Predicted to be involved in T cell receptor signaling pathway and regulation of B cell activation. Predicted to be active in cytoplasm and nucleus.

Rabbit anti-Human THEMIS2 Polyclonal Antibody

Specifications

Immunogen Information

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