Rabbit anti-Human TIPIN Polyclonal Antibody

The antibody against TIPIN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human TIPIN (NP_060328.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01441A

Number

Cat.No	ADA-01441A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TIPIN
Target Synonyms	TIPIN	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 293T, MCF7	Application	ELISA, WB

Cat.No

ADA-01441A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TIPIN

Target Synonyms

TIPIN

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 293T, MCF7

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human TIPIN (NP_060328.2).	Target Species	Human
Uniprot ID	Q9BVW5	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human TIPIN (NP_060328.2).

Target Species

Human

Uniprot ID

Q9BVW5

Immunogen Sequence

Background Information

Uniprot Id

Q9BVW5
Target Species

Human
Target Name

TIPIN
Target Full Name

TIMELESS-interacting protein
Target Function

Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.
Target Subcellular Location

Cytoplasm. Nucleus.
Target Protein Families

CSM3 family
Target Synonyms

FLJ20516; TIMELESS interacting protein; TIMELESS-interacting protein; TIPIN; TIPIN_HUMAN
Target Background

The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM, which is involved in circadian rhythm regulation, and aids in protecting cells against DNA damage and stress. Two pseudogenes and two transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human TIPIN Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human TIPIN Polyclonal Antibody Now

Related Products