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The antibody against TMOD1 was raised in rabbit using the Recombinant Human Tropomodulin-1 protein (105-359aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against TMOD1 was raised in rabbit using the Recombinant Human Tropomodulin-1 protein (105-359aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: K562 whole cell lysate, A549 whole cell lysate | All lanes: TMOD1 antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 41, 27 kDa | Observed band size: 41 kDa
| Cat.No | ADC-54891A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMOD1 |
| Target Synonyms | D9S57E TMOD, TMOD1, Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod) | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tropomodulin-1 protein (105-359aa) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P28289 |
Uniprot Id
P28289
Target Species
Human
Target Name
TMOD1
Target Full Name
Tropomodulin-1
Target Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
Tropomodulin family
Target Tissue Specificity
Highly expressed in the erythrocyte, heart and skeletal muscle.
Target Research Area
others
Target Synonyms
D9S57E; E Tmod ; E tropomodulin; E-Tmod; Erythrocyte tropomodulin; ETMOD; MGC124125; MGC124126; OTTHUMP00000021743 ; TMOD; Tmod1; TMOD1 protein; TMOD1_HUMAN; Tropomodulin 1; Tropomodulin-1
Target Background
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.
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