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The antibody against TRIM4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM4 (NP_148977.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TRIM4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM4 (NP_148977.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-12168A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRIM4 |
| Target Synonyms | RNF87; TRIM4 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HepG2, MCF7 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM4 (NP_148977.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9C037 | Immunogen Sequence |
Uniprot Id
Q9C037
Target Species
Human
Target Name
TRIM4
Target Full Name
E3 ubiquitin-protein ligase TRIM4
Target Function
E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor DDX58, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
Target Subcellular Location
Cytoplasm.
Target Protein Families
TRIM/RBCC family
Target Synonyms
RING finger protein 87; RNF 87; RNF87; TRIM4; TRIM4_HUMAN; Tripartite motif containing 4; Tripartite motif protein 4; Tripartite motif protein TRIM4; Tripartite motif-containing protein 4
Target Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.
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