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| Cat.No | ACP02146 | Target Name | SRD5A1 |
|---|---|---|---|
| Target Synonyms | SR type 1;Steroid 5-alpha-reductase 1;S5AR 1 | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-259aa |
| Mol Weight | 32.3 kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P18405 |
|---|
Uniprot Id
P18405
Target Species
Human
Target Name
SRD5A1
Target Full Name
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Target Function
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Target Subcellular Location
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Steroid 5-alpha reductase family
Target Tissue Specificity
Liver and prostate (at a low level).
Target Research Area
Neuroscience
Target Synonyms
SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; SR type 1; Steroid 5-alpha-reductase 1; S5AR 1
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