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| Cat.No | ACP01806 | Target Name | OPLAH |
|---|---|---|---|
| Target Synonyms | 5-oxo-L-prolinase;5-OPase;Pyroglutamase | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 209-302aa |
| Mol Weight | 17.4 kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14841 |
|---|
Uniprot Id
O14841
Target Species
Human
Target Name
OPLAH
Target Full Name
5-oxoprolinase
Target Function
Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
Target Involvement
5-oxoprolinase deficiency (OPLAHD)
Target Protein Families
Oxoprolinase family
Target Research Area
Metabolism
Target Synonyms
5 Opase; 5 oxo L prolinase; 5 oxoprolinase (ATP hydrolysing); 5 oxoprolinase; 5-OPase; 5-oxo-L-prolinase; 5-oxoprolinase; DKFZp434H244; OPLA; OPLA_HUMAN; oplah; OPLAHD; Pyroglutamase
Target Background
The protein encoded by this gene acts as a homodimer, using ATP hydrolysis to catalyze the conversion of 5-oxo-L-proline to L-glutamate. Defects in this gene are a cause of 5-oxoprolinase deficiency (OPLAHD).
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