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Recombinant Human Adenylate kinase isoenzyme 4, mitochondrial (AK4)

ACP20207

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20207 Target NameAK4
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-223Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP27144
Background Information
  • Uniprot Id

    P27144

  • Target Species

    Human

  • Target Name

    AK4

  • Target Full Name

    Adenylate kinase 4, mitochondrial

  • Target Function

    Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. Plays a role in controlling cellular ATP levels by regulating phosphorylation and activation of the energy sensor protein kinase AMPK. Plays a protective role in the cellular response to oxidative stress.

  • Target Subcellular Location

    Mitochondrion matrix.

  • Target Protein Families

    Adenylate kinase family, AK3 subfamily

  • Target Tissue Specificity

    Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain.

  • Target Research Area

    Metabolism

  • Target Synonyms

    Adenylate kinase 3 like 1; Adenylate kinase 3-like; adenylate kinase 4; Adenylate kinase isoenzyme 4; mitochondrial; AK3; AK3L1; AK3L2; AK4; ATP AMP transphosphorylase; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase ; KAD4_HUMAN; MGC166959; mitochondrial adenylate kinase 3; nucleoside-triphosphate adenylate kinase

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