Recombinant Human Adenylate kinase isoenzyme 5 (AK5)

Uniprot Id

Q9Y6K8

Target Species

Human

Target Name

AK5

Target Full Name

Adenylate kinase isoenzyme 5

Target Function

Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity.

Target Subcellular Location

Cytoplasm.

Target Protein Families

Adenylate kinase family

Target Tissue Specificity

Brain specific.

Target Synonyms

Adenylate kinase 5; Adenylate kinase 6; Adenylate kinase isoenzyme 5; AK 5; AK5; AK6; ATP AMP transphosphorylase 5; ATP-AMP transphosphorylase 5; KAD5; KAD5_HUMAN; MGC33326

Target Background

This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.