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Recombinant Human Ankycorbin (RAI14), Truncated

ACP11691

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11691 Target NameRAI14
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9P0K7
Background Information
  • Uniprot Id

    Q9P0K7

  • Target Species

    Human

  • Target Name

    RAI14

  • Target Full Name

    Ankycorbin

  • Target Function

    Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cell junction. Nucleus.

  • Target Tissue Specificity

    Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa.

  • Target Synonyms

    Ankycorbin; Ankyrin repeat and coiled coil structure containing protein; Ankyrin repeat and coiled-coil structure-containing protein; DKFZp564G013; KIAA1334; NORPEG; Novel retinal pigment epithelial cell protein; RAI13; RAI14; RAI14_HUMAN; Retinoic acid induced 14; Retinoic acid induced protein 14; Retinoic acid-induced protein 14

  • Target Background

    Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm.

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