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Recombinant Human Apoptosis facilitator Bcl-2-like protein 14 (BCL2L14)

ACP03161

Number
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Specifications


Cat.No ACP03161 Target NameBCL2L14
Target SynonymsBCL2L14; BCLGApoptosis facilitator Bcl-2-like protein 14; Bcl2-L-14; Apoptosis regulator Bcl-GFormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range1-327aa
Mol Weight63.6kDaProtein LengthFull length
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BZR8
Background Information
  • Uniprot Id

    Q9BZR8

  • Target Species

    Human

  • Target Name

    BCL2L14

  • Target Full Name

    Apoptosis facilitator Bcl-2-like protein 14

  • Target Function

    Plays a role in apoptosis.

  • Target Subcellular Location

    Cytoplasm.; [Isoform 1]: Cytoplasm, cytosol. Note=Diffusely distributed throughout the cytosol.; [Isoform 2]: Endomembrane system. Note=Predominantly localized to cytosolic organelles.

  • Target Protein Families

    Bcl-2 family

  • Target Tissue Specificity

    Isoform 1 is widely expressed. Isoform 2 is testis-specific.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    BCL2L14; BCLGApoptosis facilitator Bcl-2-like protein 14; Bcl2-L-14; Apoptosis regulator Bcl-G

  • Target Background

    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene.

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