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Recombinant Human ATP-binding cassette sub-family A member 6 (ABCA6), Truncated

ACP05908

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05908 Target NameABCA6
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N139
Background Information
  • Uniprot Id

    Q8N139

  • Target Species

    Human

  • Target Name

    ABCA6

  • Target Full Name

    ATP-binding cassette sub-family A member 6

  • Target Function

    Probable transporter which may play a role in macrophage lipid transport and homeostasis.

  • Target Subcellular Location

    Golgi apparatus membrane; Multi-pass membrane protein.

  • Target Protein Families

    ABC transporter superfamily, ABCA family

  • Target Tissue Specificity

    Widely expressed with higher expression in liver.

  • Target Synonyms

    ABC transporter ABCA6; ABCA 6; ABCA6; ABCA6_HUMAN; ATP binding cassette A6; ATP binding cassette sub family A (ABC1) member 6; ATP binding cassette sub family A member 6; ATP-binding cassette sub-family A member 6; EST155051; FLJ43498

  • Target Background

    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.

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