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| Cat.No | ACP06165 | Target Name | ABCB5 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q2M3G0 |
|---|
Uniprot Id
Q2M3G0
Target Species
Human
Target Name
ABCB5
Target Full Name
ATP-binding cassette sub-family B member 5
Target Function
Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
Target Tissue Specificity
Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Highly expressed in several malignant tissues: highly expressed in clinical melanomas, with low expr
Target Synonyms
ABCB 5; ABCB5; ABCB5 P-gp; ABCB5_HUMAN; ABCB5alpha; ABCB5beta; ATP binding cassette protein; ATP binding cassette sub family B (MDR/TAP) member 5; ATP binding cassette sub family B member 5; ATP-binding cassette sub-family B member 5; EST422562; P glycoprotein ABCB5; P-glycoprotein ABCB5
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