Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1)

Cat.No	ACP15045	Target Name	SUPV3L1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	23-786	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP15045

Target Name

SUPV3L1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

23-786

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q8IYB8

Background Information

Uniprot Id

Q8IYB8
Target Species

Human
Target Name

SUPV3L1
Target Full Name

ATP-dependent RNA helicase SUPV3L1, mitochondrial
Target Function

Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Target Subcellular Location

Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Target Protein Families

Helicase family
Target Tissue Specificity

Broadly expressed.
Target Synonyms

6330443E10Rik ; ATP dependent RNA helicase SUPV3L1; mitochondrial; ATP-dependent RNA helicase SUPV3L1; EC 3.6.1.; MGC109049; mitochondrial; OTTHUMP00000019719; S. Cerevisiae suppressor of var 1 3 like 1; suppressor of var1 (S.cerevisiae) 3 like 1; Suppressor of var1 3 like 1 (S. cerevisiae); Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3); Suppressor of var1 3 like 1; Suppressor of var1 3 like protein 1; Suppressor of var1 3-like protein 1; SUPV 3 L 1; SUPV3L1; SUV 3; SUV 3 L 1; SUV3; SUV3 like protein 1; SUV3-like protein 1; SUV3_HUMAN; SUV3L1
Target Background

Enables helicase activity; nucleic acid binding activity; and protein homodimerization activity. Involved in several processes, including mitochondrial RNA metabolic process; mitochondrion morphogenesis; and positive regulation of mitochondrial RNA catabolic process. Located in mitochondrial nucleoid and nucleus. Part of mitochondrial degradosome.

Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1)

Specifications

Immunogen Information

Inquire Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1) Now

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