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Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (NDST2), Truncated

ACP22951

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22951 Target NameNDST2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP52849
Background Information
  • Uniprot Id

    P52849

  • Target Species

    Human

  • Target Name

    NDST2

  • Target Full Name

    Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

  • Target Function

    Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan.

  • Target Subcellular Location

    Golgi apparatus membrane; Single-pass type II membrane protein.

  • Target Protein Families

    Sulfotransferase 1 family, NDST subfamily

  • Target Synonyms

    [Heparan sulfate]-glucosamine N-sulfotransferase; bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; Glucosaminyl N-deacetylase/N-sulfotransferase 2; glucosaminyl N-deacetylase/N-sulphotransferase 2; heparan glucosaminyl N-deacetylase/N-sulfotransferase 2; heparan N-sulfotransferase 2; heparan sulfate N-deacetylase/N-sulfotransferase 2; Heparan sulfate N-sulfotransferase 2; HSST2; mastocytoma N-deacetylase/N-sulfotransferase; Mndns; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; N-heparan sulfate sulfotransferase 2; N-HSST 2; NDST-2; NDST2; NDST2_HUMAN; NST2

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