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| Cat.No | ACP22951 | Target Name | NDST2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P52849 |
|---|
Uniprot Id
P52849
Target Species
Human
Target Name
NDST2
Target Full Name
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2
Target Function
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Sulfotransferase 1 family, NDST subfamily
Target Synonyms
[Heparan sulfate]-glucosamine N-sulfotransferase; bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; Glucosaminyl N-deacetylase/N-sulfotransferase 2; glucosaminyl N-deacetylase/N-sulphotransferase 2; heparan glucosaminyl N-deacetylase/N-sulfotransferase 2; heparan N-sulfotransferase 2; heparan sulfate N-deacetylase/N-sulfotransferase 2; Heparan sulfate N-sulfotransferase 2; HSST2; mastocytoma N-deacetylase/N-sulfotransferase; Mndns; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; N-heparan sulfate sulfotransferase 2; N-HSST 2; NDST-2; NDST2; NDST2_HUMAN; NST2
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