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| Cat.No | ACP11543 | Target Name | KCTD10 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-313 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H3F6 |
|---|
Uniprot Id
Q9H3F6
Target Species
Human
Target Name
KCTD10
Target Full Name
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3
Target Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome.
Target Subcellular Location
Nucleus.
Target Protein Families
BACURD family
Target Synonyms
KCTD10; ULR061; MSTP028BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3; hBACURD3; BTB/POZ domain-containing protein KCTD10; Potassium channel tetramerization domain-containing protein 10
Target Background
The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene.
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