Recombinant Human Cadherin-9 (CDH9), Truncated

Uniprot Id

Q9ULB4

Target Species

Human

Target Name

CDH9

Target Full Name

Cadherin-9

Target Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Target Research Area

Neuroscience

Target Synonyms

CADH9_HUMAN; Cadherin 9 type 2; Cadherin-9; Cadherin9; CDH 9; CDH9; T1 cadherin

Target Background

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.