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| Cat.No | ACP06184 | Target Name | PDE3B |
|---|---|---|---|
| Target Synonyms | 5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, homolog of; Pde3b; PDE3B_HUMAN; Phosphodiesterase 3B; Phosphodiesterase 3B cGMP inhibited, rat | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13370 |
|---|
Uniprot Id
Q13370
Target Species
Human
Target Name
PDE3B
Target Full Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
Target Function
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Cyclic nucleotide phosphodiesterase family, PDE3 subfamily
Target Tissue Specificity
Abundant in adipose tissues.
Target Synonyms
5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodiesterase; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase B; Cyclic GMP-inhibited phosphodiesterase B; Cyclic nucleotide phosphodiesterase; HcGIP1; HcGIP1, rat, homolog of; Pde3b; PDE3B_HUMAN; Phosphodiesterase 3B; Phosphodiesterase 3B cGMP inhibited
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