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Recombinant Human Chromodomain-helicase-DNA-binding protein 1-like (CHD1L), Truncated

ACP02363

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Specifications

Cat.No	ACP02363	Target Name	CHD1L
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	704-897aa	Mol Weight	37.3kDa
Protein Length	Partial	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q86WJ1

Background Information

Uniprot Id

Q86WJ1
Target Species

Human
Target Name

CHD1L
Target Full Name

Chromodomain-helicase-DNA-binding protein 1-like
Target Function

DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
Target Subcellular Location

Nucleus.
Target Protein Families

SNF2/RAD54 helicase family
Target Tissue Specificity

Frequently overexpressed in hepatomacellular carcinomas.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

ALC1; Amplified in liver cancer 1; Amplified in liver cancer protein 1; chd1l; CHD1L_HUMAN; CHDL; Chromodomain helicase DNA binding protein 1 like; Chromodomain-helicase-DNA-binding protein 1-like; FLJ22530
Target Background

This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Overexpression of this gene has been linked to several types of cancers.

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Recombinant Human Chromodomain-helicase-DNA-binding protein 1-like (CHD1L), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Chromodomain-helicase-DNA-binding protein 1-like (CHD1L), Truncated Now

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