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Recombinant Human Chromosome transmission fidelity protein 8 homolog (CHTF8)

ACP20277

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Specifications

Cat.No	ACP20277	Target Name	CHTF8
Target Synonyms	CHTF8; CTF8; Chromosome transmission fidelity protein 8 homolog; hCTF8	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-121
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P0CG13

Background Information

Uniprot Id

P0CG13
Target Species

Human
Target Name

CHTF8
Target Full Name

Chromosome transmission fidelity protein 8 homolog
Target Function

Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DSCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair, recombination and chromosome cohesion reactions with replication fork progression
Target Subcellular Location

Nucleus.
Target Protein Families

CTF8 family
Target Synonyms

CHTF8; CTF8; Chromosome transmission fidelity protein 8 homolog; hCTF8

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Recombinant Human Chromosome transmission fidelity protein 8 homolog (CHTF8)

Specifications

Immunogen Information

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