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Recombinant Human Cleavage and polyadenylation specificity factor subunit 2 (CPSF2)

ACP10205

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10205 Target NameCPSF2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-782Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9P2I0
Background Information
  • Uniprot Id

    Q9P2I0

  • Target Species

    Human

  • Target Name

    CPSF2

  • Target Full Name

    Cleavage and polyadenylation specificity factor subunit 2

  • Target Function

    Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily

  • Target Synonyms

    Cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specific factor 2; 100kDa; Cleavage and polyadenylation specificity factor 100 kDa subunit; Cleavage and polyadenylation specificity factor subunit 2; CPSF 100 kDa subunit; CPSF 2; CPSF100; Cpsf2; CPSF2_HUMAN; KIAA1367; zgc:92484

  • Target Background

    Predicted to enable RNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Located in membrane. Part of mRNA cleavage and polyadenylation specificity factor complex.

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