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Recombinant Human Coiled-coil domain-containing protein 78 (CCDC78)

ACP22060

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Specifications

Cat.No	ACP22060	Target Name	CCDC78
Target Synonyms	CCDC78; C16orf25; JFP10Coiled-coil domain-containing protein 78; hsCCDC78	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-438
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	A2IDD5

Background Information

Uniprot Id

A2IDD5
Target Species

Human
Target Name

CCDC78
Target Full Name

Coiled-coil domain-containing protein 78
Target Function

Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for CEP152 localization to the deuterosome.
Target Involvement

Myopathy, centronuclear, 4 (CNM4)
Target Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, perinuclear region. Cell membrane, sarcolemma. Sarcoplasmic reticulum. Note=Localizes to centrioles and deuterosome. Found primarily in the perinuclear region as well as along the sarcolemmal membrane and in reticular pattern within the sarcoplasm.
Target Protein Families

CCDC78 family
Target Tissue Specificity

Expressed primarily in skeletal muscle.
Target Synonyms

CCDC78; C16orf25; JFP10Coiled-coil domain-containing protein 78; hsCCDC78

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Recombinant Human Coiled-coil domain-containing protein 78 (CCDC78)

Specifications

Immunogen Information

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