Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The recombinant Human COG5 was expressed with the amino acid range of 1-257. The theoretical molecular weight of the COG5 protein is 33.8 kDa. This COG5 protein is produced using e.coli expression system. The COG5 coding gene included the N-terminal 10xHis tag, which simplifies the detection and purification processes of the recombinant COG5 protein in following stages of expression and purification.Conserved oligomeric Golgi complex subunit 5 (COG5) is a part of the COG complex, which is involved in maintaining the structure and function of the Golgi apparatus. COG5 specifically plays a role in tethering vesicles and facilitating the intra-Golgi transport of proteins. Mutations in the COG5 gene can lead to defects in protein glycosylation and result in congenital disorders of glycosylation (CDG), affecting various physiological processes. Research areas involving COG5 include investigating its role in intracellular trafficking, glycosylation disorders, and cellular homeostasis. Understanding COG5's functions contributes to insights into fundamental cellular processes and potential therapeutic targets for related disorders.
The recombinant Human COG5 was expressed with the amino acid range of 1-257. The theoretical molecular weight of the COG5 protein is 33.8 kDa. This COG5 protein is produced using e.coli expression system. The COG5 coding gene included the N-terminal 10xHis tag, which simplifies the detection and purification processes of the recombinant COG5 protein in following stages of expression and purification.Conserved oligomeric Golgi complex subunit 5 (COG5) is a part of the COG complex, which is involved in maintaining the structure and function of the Golgi apparatus. COG5 specifically plays a role in tethering vesicles and facilitating the intra-Golgi transport of proteins. Mutations in the COG5 gene can lead to defects in protein glycosylation and result in congenital disorders of glycosylation (CDG), affecting various physiological processes. Research areas involving COG5 include investigating its role in intracellular trafficking, glycosylation disorders, and cellular homeostasis. Understanding COG5’s functions contributes to insights into fundamental cellular processes and potential therapeutic targets for related disorders.
| Cat.No | ACP01712 | Target Name | COG5 |
|---|---|---|---|
| Target Synonyms | (COG complex subunit 5)(13S Golgi transport complex 90 kDa subunit)(GTC-90)(Component of oligomeric Golgi complex 5)(Golgi transport complex 1) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-257aa |
| Mol Weight | 33.8 kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UP83 |
|---|
Uniprot Id
Q9UP83
Target Species
Human
Target Name
COG5
Target Full Name
Conserved oligomeric Golgi complex subunit 5
Target Function
Required for normal Golgi function.
Target Involvement
Congenital disorder of glycosylation 2I (CDG2I)
Target Subcellular Location
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein.
Target Protein Families
COG5 family
Target Research Area
Signal Transduction
Target Synonyms
COG5; GOLTC1; GTC90Conserved oligomeric Golgi complex subunit 5; COG complex subunit 5; 13S Golgi transport complex 90 kDa subunit; GTC-90; Component of oligomeric Golgi complex 5; Golgi transport complex 1
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
