Home Products Recombinant Human CUGBP Elav-like family member 4 (CELF4)

Recombinant Human CUGBP Elav-like family member 4 (CELF4)

ACP10707

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Specifications

Cat.No	ACP10707	Target Name	CELF4
Target Synonyms	CELF4; BRUNOL4; CUGBP Elav-like family member 4; CELF-4; Bruno-like protein 4; CUG-BP- and ETR-3-like factor 4; RNA-binding protein BRUNOL-4	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-486
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BZC1

Background Information

Uniprot Id

Q9BZC1
Target Species

Human
Target Name

CELF4
Target Full Name

CUGBP Elav-like family member 4
Target Function

RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Target Subcellular Location

Nucleus. Cytoplasm.
Target Protein Families

CELF/BRUNOL family
Target Tissue Specificity

Ubiquitous. Strongly expressed in the cerebellum, hippocampus, amygdala, temporal and frontal cortex and frontal lobes.
Target Synonyms

CELF4; BRUNOL4; CUGBP Elav-like family member 4; CELF-4; Bruno-like protein 4; CUG-BP- and ETR-3-like factor 4; RNA-binding protein BRUNOL-4

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Recombinant Human CUGBP Elav-like family member 4 (CELF4)

Specifications

Immunogen Information

Inquire Recombinant Human CUGBP Elav-like family member 4 (CELF4) Now

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