Recombinant Human Cysteine sulfinic acid decarboxylase (CSAD)

Uniprot Id

Q9Y600

Target Species

Human

Target Name

CSAD

Target Full Name

Cysteine sulfinic acid decarboxylase

Target Function

Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is 3-sulfino-L-alanine. Does not exhibit any decarboxylation activity toward glutamate.

Target Protein Families

Group II decarboxylase family

Target Tissue Specificity

Expressed in liver and brain. Also expressed in both astrocytes and neurons, but lower levels are expressed in astrocytes.

Target Synonyms

Csad; CSAD_HUMAN; CSD; Cysteine sulfinic acid decarboxylase; Cysteine-sulfinate decarboxylase; Sulfinoalanine decarboxylase

Target Background

This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.