Recombinant Human Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L)

Cat.No	ACP03466	Target Name	COX7A2L
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	1-114aa	Mol Weight	39.6kDa
Protein Length	Full length	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP03466

Target Name

COX7A2L

Form

Liquid or Lyophilized powder

Expression System

E.coli

Expression Range

1-114aa

Mol Weight

39.6kDa

Protein Length

Full length

Purity

Greater than 90% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	O14548

Background Information

Uniprot Id

O14548
Target Species

Human
Target Name

COX7A2L
Target Full Name

Cytochrome c oxidase subunit 7A2-like, mitochondrial
Target Function

Involved in the regulation of oxidative phosphorylation and energy metabolism. Necessary for the assembly of mitochondrial respiratory supercomplex.
Target Subcellular Location

Mitochondrion inner membrane.
Target Protein Families

Cytochrome c oxidase VIIa family
Target Research Area

Signal Transduction
Target Synonyms

COX7a related protein; COX7a-related protein; COX7A2L; COX7AR; COX7R_HUMAN; COX7RP; Cytochrome c oxidase subunit 7A-related protein; cytochrome c oxidase subunit 7A-related protein; mitochondrial; Cytochrome c oxidase subunit 7A2 like; cytochrome c oxidase subunit VII-related protein; cytochrome c oxidase subunit VIIa polypeptide 2 like; Cytochrome c oxidase subunit VIIa related protein; mitochondrial; Cytochrome c oxidase subunit VIIa-related protein; EB1; Estrogen receptor binding CpG island; mitochondrial; SIG81
Target Background

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.

Recombinant Human Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L)

Specifications

Immunogen Information

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