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Recombinant Human Cytochrome c-type heme lyase (HCCS)

ACP03553

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP03553 Target NameHCCS
FormLiquid or Lyophilized powderExpression SystemE.coli
Expression Range1-268aaMol Weight57.6kDa
Protein LengthFull lengthPurityGreater than 90% as determined by SDS-PAGE.
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP53701
Background Information
  • Uniprot Id

    P53701

  • Target Species

    Human

  • Target Name

    HCCS

  • Target Full Name

    Holocytochrome c-type synthase

  • Target Function

    Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.

  • Target Involvement

    Linear skin defects with multiple congenital anomalies 1 (LSDMCA1)

  • Target Subcellular Location

    Mitochondrion inner membrane. Membrane; Lipid-anchor.

  • Target Protein Families

    Cytochrome c-type heme lyase family

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    CCHL; CCHL_HUMAN; cytochrome c heme-lyase; Cytochrome c-type heme lyase; DKFZp779I1858; EC 4.4.1.17; Hccs; Holocytochrome c synthase (cytochrome c heme lyase) ; Holocytochrome c synthase; Holocytochrome c type synthase ; Holocytochrome c-type synthase; MCOPS7 ; OTTHUMP00000022903; OTTHUMP00000022904; OTTHUMP00000022905; OTTMUSP00000021173; OTTMUSP00000021174; RGD1563855; RP23-37L2.1

  • Target Background

    The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.

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