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| Cat.No | ACP16841 | Target Name | DACT2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-774 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5SW24 |
|---|
Uniprot Id
Q5SW24
Target Species
Human
Target Name
DACT2
Target Full Name
Dapper homolog 2
Target Function
Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling.
Target Protein Families
Dapper family
Target Synonyms
bA503C24.7; C6orf116; Chromosome 6 open reading frame 116 ; Dact2; DACT2_HUMAN; Dapper antagonist of beta catenin homolog 2; Dapper antagonist of beta catenin homolog 2 Xenopus laevis; Dapper homolog 2 antagonist of beta catenin ; Dapper homolog 2 antagonist of beta catenin xenopus ; Dapper homolog 2; DAPPER2; DPR2; FLJ31232 ; MGC133141; MGC133142 ; RP11 503C24.7
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