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| Cat.No | ACP12839 | Target Name | DOCK4 |
|---|---|---|---|
| Target Synonyms | Dedicator of cytokinesis protein 4; Dock4; DOCK4_HUMAN; KIAA0716 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N1I0 |
|---|
Uniprot Id
Q8N1I0
Target Species
Human
Target Name
DOCK4
Target Full Name
Dedicator of cytokinesis protein 4
Target Function
Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration.; Has a higher guanine nucleotide exchange factor activity compared to other isoforms.
Target Subcellular Location
Cell membrane. Cell projection. Cytoplasm, cytosol.
Target Protein Families
DOCK family
Target Tissue Specificity
Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary.; [Isoform 2]: May be specifically expressed in the brain and eye.
Target Synonyms
Dedicator of cytokinesis protein 4; Dock4; DOCK4_HUMAN; KIAA0716
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