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Recombinant Human Double C2-like domain-containing protein beta (DOC2B)

ACP18148

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Specifications

Cat.No	ACP18148	Target Name	DOC2B
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-412	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q14184

Background Information

Uniprot Id

Q14184
Target Species

Human
Target Name

DOC2B
Target Full Name

Double C2-like domain-containing protein beta
Target Function

Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.
Target Subcellular Location

Cytoplasm. Cytoplasmic granule. Cell membrane; Peripheral membrane protein.
Target Tissue Specificity

Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (at protein level).
Target Synonyms

Doc2 beta; Doc2-beta; Doc2b; DOC2B_HUMAN; DOC2BL; Double C2 like domain containing protein beta; Double C2 like domains beta; Double C2 like domains beta like; Double C2-like domain-containing protein beta; OTTMUSP00000006522; RP23 78H4.2

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Recombinant Human Double C2-like domain-containing protein beta (DOC2B)

Specifications

Immunogen Information

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