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| Cat.No | ACP16553 | Target Name | DUX4L9 |
|---|---|---|---|
| Target Synonyms | DUX4L9; DUX4CDouble homeobox protein 4C; Double homeobox protein 4; centromeric; DUX4c; Double homeobox protein 4-like protein 9 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-374 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6RFH8 |
|---|
Uniprot Id
Q6RFH8
Target Species
Human
Target Name
DUX4L9
Target Full Name
Double homeobox protein 4C
Target Function
May be involved in transcriptional regulation. Down-regulates MYOD1 expression and may up-regulate MYF5 expression. May regulate microRNA (miRNA) transcription, upregulating the expression of some myogenic miRNAs, including MIR1-1, MIR133A2, MIR133B and MIR206. Impairs the differentiation of myoblasts and may be involved in muscle regeneration.
Target Involvement
Up-regulated in myoblasts of facioscapulohumeral muscular dystrophy (FSHD) patients (at protein level).
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in muscles, as well as in primary myoblasts and myotubes (at protein level).
Target Synonyms
DUX4L9; DUX4CDouble homeobox protein 4C; Double homeobox protein 4; centromeric; DUX4c; Double homeobox protein 4-like protein 9
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