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| Cat.No | ACP13942 | Target Name | DNAAF1 |
|---|---|---|---|
| Target Synonyms | DNAAF1; LRRC50Dynein assembly factor 1; axonemal; Leucine-rich repeat-containing protein 50 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-725 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NEP3 |
|---|
Uniprot Id
Q8NEP3
Target Species
Human
Target Name
DNAAF1
Target Full Name
Dynein axonemal assembly factor 1
Target Function
Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
Target Involvement
Ciliary dyskinesia, primary, 13 (CILD13)
Target Subcellular Location
Cell projection, cilium. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=In HEK293T cells, it is diffusely cytoplasmic and concentrates at the mitotic spindle poles, while in MDCK cells, it localizes in the cilium. In vivo, this protein is probably restricted to the cilium.
Target Protein Families
DNAAF1 family
Target Tissue Specificity
Mainly expressed in trachea and testis.
Target Synonyms
DNAAF1; LRRC50Dynein assembly factor 1; axonemal; Leucine-rich repeat-containing protein 50
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