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| Cat.No | ACP07973 | Target Name | RNF149 |
|---|---|---|---|
| Target Synonyms | RNF149; DNAPTP2; E3 ubiquitin-protein ligase RNF149; DNA polymerase-transactivated protein 2; RING finger protein 149; RING-type E3 ubiquitin transferase RNF149 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NC42 |
|---|
Uniprot Id
Q8NC42
Target Species
Human
Target Name
RNF149
Target Full Name
E3 ubiquitin-protein ligase RNF149
Target Function
E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
Target Subcellular Location
Membrane; Single-pass membrane protein.
Target Synonyms
RNF149; DNAPTP2; E3 ubiquitin-protein ligase RNF149; DNA polymerase-transactivated protein 2; RING finger protein 149; RING-type E3 ubiquitin transferase RNF149
Target Background
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Located in membrane.
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