Home Products Recombinant Human E3 ubiquitin-protein ligase RNF19B (RNF19B), Truncated

Recombinant Human E3 ubiquitin-protein ligase RNF19B (RNF19B), Truncated

ACP08162

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Specifications

Cat.No	ACP08162	Target Name	RNF19B
Target Synonyms	RNF19B; IBRDC3; NKLAM; E3 ubiquitin-protein ligase RNF19B; IBR domain-containing protein 3; Natural killer lytic-associated molecule; RING finger protein 19B	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6ZMZ0

Background Information

Uniprot Id

Q6ZMZ0
Target Species

Human
Target Name

RNF19B
Target Full Name

E3 ubiquitin-protein ligase RNF19B
Target Function

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death.
Target Subcellular Location

Cytoplasmic granule membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

RBR family, RNF19 subfamily
Target Tissue Specificity

Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in natural killer cells (at protein level). Ubiquitously expressed with high expression in testis.
Target Synonyms

RNF19B; IBRDC3; NKLAM; E3 ubiquitin-protein ligase RNF19B; IBR domain-containing protein 3; Natural killer lytic-associated molecule; RING finger protein 19B

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Recombinant Human E3 ubiquitin-protein ligase RNF19B (RNF19B), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human E3 ubiquitin-protein ligase RNF19B (RNF19B), Truncated Now

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