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Recombinant Human E3 ubiquitin-protein ligase TRIM68 (TRIM68)

ACP16596

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16596 Target NameTRIM68
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-485Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6AZZ1
Background Information
  • Uniprot Id

    Q6AZZ1

  • Target Species

    Human

  • Target Name

    TRIM68

  • Target Full Name

    E3 ubiquitin-protein ligase TRIM68

  • Target Function

    Functions as a ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.

  • Target Subcellular Location

    Cytoplasm, perinuclear region. Nucleus. Note=Colocalized with AR in nucleus.

  • Target Protein Families

    TRIM/RBCC family

  • Target Tissue Specificity

    Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.

  • Target Synonyms

    TRIM68; GC109; RNF137; SS56; E3 ubiquitin-protein ligase TRIM68; EC 2.3.2.27; RING finger protein 137; RING-type E3 ubiquitin transferase TRIM68; SSA protein SS-56; SS-56; Tripartite motif-containing protein 68

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