Recombinant Human Early placenta insulin-like peptide (INSL4)

Uniprot Id

Q14641

Target Species

Human

Target Name

INSL4

Target Full Name

Early placenta insulin-like peptide

Target Function

May play an important role in trophoblast development and in the regulation of bone formation.

Target Subcellular Location

Secreted.

Target Protein Families

Insulin family

Target Tissue Specificity

Expressed in placenta, uterus and in fetal perichondrium. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells.

Target Synonyms

early placenta insulin like peptide (EPIL) ; Early placenta insulin like peptide A chain; Early placenta insulin like peptide; Early placenta insulin like peptide B chain; Early placenta insulin-like peptide A chain; EPIL; INSL4; INSL4_HUMAN; insulin like 4 ; insulin like 4 (placenta); Insulin like peptide 4; Insulin-like peptide 4; OTTHUMP00000021025; Placentin

Target Background

INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast.