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In expressing the recombinant Human EDIL3 protein, baculovirus cells are transfected with a DNA expression vector that harbors the gene for the desired protein (24-480aa). The cultured cells then express the intended protein. The protein is equipped with a C-terminal 6xHis tag. The recombinant Human EDIL3 protein is collected and purified from the cell lysate through affinity purification, achieving a purity surpassing 85%, as confirmed by SDS-PAGE.
In expressing the recombinant Human EDIL3 protein, baculovirus cells are transfected with a DNA expression vector that harbors the gene for the desired protein (24-480aa). The cultured cells then express the intended protein. The protein is equipped with a C-terminal 6xHis tag. The recombinant Human EDIL3 protein is collected and purified from the cell lysate through affinity purification, achieving a purity surpassing 85%, as confirmed by SDS-PAGE.
| Cat.No | ACP01636 | Target Name | EDIL3 |
|---|---|---|---|
| Target Synonyms | (Developmentally-regulated endothelial cell locus 1 protein)(Integrin-binding protein DEL1) | Form | Liquid or Lyophilized powder |
| Expression System | Baculovirus | Expression Range | 24-480aa |
| Mol Weight | 57.0 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43854 |
|---|
Uniprot Id
O43854
Target Species
Human
Target Name
EDIL3
Target Full Name
EGF-like repeat and discoidin I-like domain-containing protein 3
Target Function
Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
Target Subcellular Location
Secreted.
Target Research Area
Cardiovascular
Target Synonyms
DEL1 ; Developmental endothelial locus 1 ; Developmentally regulated endothelial cell locus 1 protein; Developmentally-regulated endothelial cell locus 1 protein; Edil3; EDIL3_HUMAN; EGF like repeat and discoidin I like domain containing protein 3; EGF like repeats and discoidin I like domains 3; EGF like repeats and discoidin I like domains protein 3; EGF-like repeat and discoidin I-like domain-containing protein 3; Integrin binding protein DEL1; Integrin-binding protein DEL1
Target Background
The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior.
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