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| Cat.No | ACP13810 | Target Name | ERP27 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 26-273 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96DN0 |
|---|
Uniprot Id
Q96DN0
Target Species
Human
Target Name
ERP27
Target Full Name
Endoplasmic reticulum resident protein 27
Target Function
Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates. Binds protein substrates via a hydrophobic pocket in the C-terminal domain. May play a role in the unfolded stress response.
Target Subcellular Location
Endoplasmic reticulum lumen.
Target Protein Families
Protein disulfide isomerase family
Target Synonyms
C12orf46 ; Chromosome 12 open reading frame 46; Endoplasmic reticulum protein 27; Endoplasmic reticulum protein 27 kDa ; Endoplasmic reticulum resident protein 27; Endoplasmic reticulum resident protein ERp27; ER protein 27; ERp 27; ERp27; ERP27_HUMAN; FLJ32115; PDIA8; Protein disulfide isomerase family A; member 8
Target Background
This gene encodes a noncatalytic member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. The canonical protein has an N-terminal signal sequence, two thioredoxin (TRX)-like domains and a C-terminal ER-retention sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which lack domains present in the canonical protein.
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