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| Cat.No | ACP12815 | Target Name | EID2 |
|---|---|---|---|
| Target Synonyms | EID2; CRI2EP300-interacting inhibitor of differentiation 2; EID-2; CREBBP/EP300 inhibitor 2; EID-1-like inhibitor of differentiation 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-236 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N6I1 |
|---|
Uniprot Id
Q8N6I1
Target Species
Human
Target Name
EID2
Target Full Name
EP300-interacting inhibitor of differentiation 2
Target Function
Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Most abundantly expressed in placenta. Highly expressed in liver, brain, heart, skeletal muscle, and kidney.
Target Synonyms
EID2; CRI2EP300-interacting inhibitor of differentiation 2; EID-2; CREBBP/EP300 inhibitor 2; EID-1-like inhibitor of differentiation 2
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